Publications

Zhou D, Ota K, Nardin C, Feldman M, Widman A, Wind O, Simon A, Reilly M, Levin LR, Buck J et al..  2018.  Mammalian pigmentation is regulated by a distinct cAMP-dependent mechanism that controls melanosome pH.. Sci Signal. 11(555)

Ramos-Espiritu L, Kleinboelting S, Navarrete FA, Alvau A, Visconti PE, Valsecchi F, Starkov A, Manfredi G, Buck H, Adura C et al..  2016.  Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase.. Nat Chem Biol. 12(10):838-44.

Ramos-Espiritu L, Diaz A, Nardin C, Saviola AJ, Shaw F, Plitt T, Yang X, Wolchok J, Pirog EC, Desman G et al..  2016.  The metabolic/pH sensor soluble adenylyl cyclase is a tumor suppressor protein.. Oncotarget. 7(29):45597-45607.

Zippin JH, Chen Y, Straub SG, Hess KC, Diaz A, Lee D, Tso P, Holz GG, Sharp GWG, Levin LR et al..  2013.  CO2/HCO3(-)- and calcium-regulated soluble adenylyl cyclase as a physiological ATP sensor.. J Biol Chem. 288(46):33283-91.

Zippin JH, Chadwick PA, Levin LR, Buck J, Magro CM.  2010.  Soluble adenylyl cyclase defines a nuclear cAMP microdomain in keratinocyte hyperproliferative skin diseases.. J Invest Dermatol. 130(5):1279-87.

Ramos LS, Zippin JHale, Kamenetsky M, Buck J, Levin LR.  2008.  Glucose and GLP-1 stimulate cAMP production via distinct adenylyl cyclases in INS-1E insulinoma cells.. J Gen Physiol. 132(3):329-38.

Wu KY, Zippin JH, Huron DR, Kamenetsky M, Hengst U, Buck J, Levin LR, Jaffrey SR.  2006.  Soluble adenylyl cyclase is required for netrin-1 signaling in nerve growth cones.. Nat Neurosci. 9(10):1257-64.

Stessin AM, Zippin JH, Kamenetsky M, Hess KC, Buck J, Levin LR.  2006.  Soluble adenylyl cyclase mediates nerve growth factor-induced activation of Rap1.. J Biol Chem. 281(25):17253-8.

Hess KC, Jones BH, Marquez B, Chen Y, Ord TS, Kamenetsky M, Miyamoto C, Zippin JH, Kopf GS, Suarez SS et al..  2005.  The "soluble" adenylyl cyclase in sperm mediates multiple signaling events required for fertilization.. Dev Cell. 9(2):249-59.

Zippin JH, Farrell J, Huron D, Kamenetsky M, Hess KC, Fischman DA, Levin LR, Buck J.  2004.  Bicarbonate-responsive "soluble" adenylyl cyclase defines a nuclear cAMP microdomain.. J Cell Biol. 164(4):527-34.

Zippin JH, Chen Y, Nahirney P, Kamenetsky M, Wuttke MS, Fischman DA, Levin LR, Buck J.  2003.  Compartmentalization of bicarbonate-sensitive adenylyl cyclase in distinct signaling microdomains.. FASEB J. 17(1):82-4.