The primary interest of the lab is understanding how microenvironmental changes such as pH and metabolism impact melanocyte, keratinocyte, and T cell biology. One focus of the lab is the study of non-canonical cAMP signaling pathways in skin disease through which we have revealed new mechanisms that control organelle pH, tumor suppression, and T cell differentiation. We use a variety of cellular and mouse model systems and technologies such as microscopy, high-throughput sequencing techniques, and LC/MS.
Affiliations
Our lab works closely with groups within the Meyer Cancer Center; the Englander Institute of Precision Medicine at Weill Cornell Medicine; and Memorial Sloan Kettering Cancer Center.
Job Opportunities
1 sentence (approx. 25 words) teaser about your team. Example: The Cantley lab welcomes a diverse set of talents and fosters an interdisciplinary approach in its attempts to translate fundamental scientific discoveries into clinical innovations. To insert your text: Click “Customize this Page” at bottom of the window. Scroll down to the appropriate box you would like to edit and click the box with the gears logo. Insert your text in the Text field. Click “Update Preview” and then “Save.” Click “Save” in the black bar at the bottom of the window to save all changes.